JAMA Network Open
Original Investigation
Neurology
July 8, 2022
Michael J. Bell, MD; Bedda L. Rosario, PhD; Patrick M. Kochanek, MD; P. David Adelson, MD; Kevin P. Morris, MD; Alicia K. Au, MD; Michelle Schober, MD; Warwick Butt, MD; Richard J. Edwards, MD; Jerry Zimmerman, MD; Jose Pineda, MD; Truc M. Le, MD; Nathan Dean, MD; Michael J. Whalen, MD; Anthony Figaji, MMED; James Luther, MS; Sue R. Beers, PhD; Deepak K. Gupta, MCH, PhD; Jessica Carpenter, MD; Sandra Buttram, MD; Stephen R. Wisniewski, PhD; Approaches and Decisions for Acute Pediatric TBI (ADAPT) Investigators
open access
JAMA Netw Open. 2022; 5(7):e2220969. 10.1001/jamanetworkopen.2022.20969
This comparative effectiveness study assesses the associations of cerebrospinal fluid diversion with Glasgow Outcome Score–Extended for Pediatrics and decreased intracranial pressure in children with severe traumatic brain injury.
JAMA Network Open
Original Investigation
Pediatrics
March 10, 2022
Patrick M. Kochanek, MD; P. David Adelson, MD; Bedda L. Rosario, PhD; James Hutchison, MD; Nikki Miller Ferguson, MD; Peter Ferrazzano, MD; Nicole O’Brien, MD; John Beca, MD; Ajit Sarnaik, MD; Kerri LaRovere, MD; Tellen D. Bennett, MD, MS; Akash Deep, MD; Deepak Gupta, MCH, PhD; F. Anthony Willyerd, MD; Shiyao Gao, PhD; Stephen R. Wisniewski, PhD; Michael J. Bell, MD; ADAPT Investigators
open access
JAMA Netw Open. 2022; 5(3):e220891. 10.1001/jamanetworkopen.2022.0891
This comparative effectiveness research study of children with traumatic brain injury (TBI) compares intracranial pressure and cerebral perfusion pressure outcomes of bolus administration of hypertonic saline and mannitol.
JAMA Surgery
Original Investigation
May 8, 2019
Daniel W. Spaite, MD; Bentley J. Bobrow, MD; Samuel M. Keim, MD, MS; Bruce Barnhart, RN, CEP; Vatsal Chikani, MPH; Joshua B. Gaither, MD; Duane Sherrill, PhD; Kurt R. Denninghoff, MD; Terry Mullins, MPH, MBA; P. David Adelson, MD; Amber D. Rice, MD, MS; Chad Viscusi, MD; Chengcheng Hu, PhD
free access
online only
JAMA Surg. 2019; 154(7):e191152. 10.1001/jamasurg.2019.1152
This study evaluates the association of implementing the nationally vetted, evidence-based, prehospital treatment guidelines with outcomes in moderate, severe, and critical traumatic brain injury.
JAMA Surgery
Original Investigation
April 1, 2017
Daniel W. Spaite, MD; Chengcheng Hu, PhD; Bentley J. Bobrow, MD; Vatsal Chikani, MPH; Duane Sherrill, PhD; Bruce Barnhart, RN, CEP; Joshua B. Gaither, MD; Kurt R. Denninghoff, MD; Chad Viscusi, MD; Terry Mullins, MBA; P. David Adelson, MD
free access
JAMA Surg. 2017; 152(4):360-368. 10.1001/jamasurg.2016.4686
This secondary analysis of the Excellence in Prehospital Injury Care Traumatic Brain Injury Study evaluates whether a statistically supportable threshold between systolic pressure and mortality exists in patients with traumatic brain injury.